A comparative analysis of dominant dietary patterns in patients with and without oral squamous cell carcinoma

Razavi, Seyed Mohammad; Askari, Gholamreza; Zahiri, Zahra; Heidari, Zahra; Keshani, Forooz

A comparative analysis of dominant dietary patterns in patients with and without oral squamous cell carcinoma

Authors

¹ Department of Oral and Maxillofacial Pathology, Dental Implants Research Center, School of Dentistry, Dental Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

² Department of Community Nutrition, School of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, Iran

³ Department of Oral and Maxillofacial Pathology, Students Research Committee, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran

⁴ Department of Epidemiology and Biostatistics, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran

⁵ Department of Oral and Maxillofacial Pathology, Dental Research Center, School of Dentistry, Dental Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background: As a modifiable risk factor, nutrition plays a pivotal role in the prevention or delay of oral squamous cell carcinoma (OSCC). This study was aimed to investigate and compare the dominant dietary patterns in the patients with and without OSCC.
Materials and Methods: This case-control study evaluated the usual dietary intake of 80 cases and 120 controls during 2019–2020 using the 117-item Food Frequency Questionnaire, with confirmed validity and reliability. Factor analysis was used to detect the dominant dietary patterns. Data analysis was done by SPSS (version 21) using the Chi-square test, ANOVA, logistic regression analysis, and independent t-test (P < 0.05).
Results: Three dietary patterns were identified, including the western dietary pattern, health dietary pattern, and traditional dietary pattern. The odds ratio (OR) = 1.181 and confidence interval (CI) = 0.671 and 2.082 were found for the western dietary pattern, OR = 1.087 and CI = 0.617 and 1.914 were detected for the healthy dietary pattern, and OR = 0.846 and CI = 0.480 and 1.491 were reported for the traditional dietary pattern. No significant difference was found between the study groups in the dietary pattern and the risk of disease. This relationship remained insignificant after adjustment for the energy intake and confounding factors.
Conclusion: There was no significant relationship between adherence to healthy, traditional, and western dietary patterns and OSCC. Consumption of vegetables and nuts had a protective role against the disease, but risky behaviors such as smoking and alcohol use were directly associated with the incidence of the disease.

Keywords

References

1.	Rodríguez-Molinero J, Migueláñez-Medrán BD, Puente-Gutiérrez C, Delgado-Somolinos E, Martín Carreras-Presas C, Fernández-Farhall J, et al. Association between oral cancer and diet: An update. Nutrients 2021;13:1299.
2.	Neville BW, Damm DD, Allen CM, Bouqout JE. Oral and Maxillofacial Pathology. 4^th ed. Philadelphia: WB Saunders Co; 2016. p. 374-89.
3.	Azimi S, Ghorbani Z, Tennant M, Kruger E, Safiaghdam H, Rafieian N. Population survey of knowledge about oral cancer and related factors in the capital of Iran. J Cancer Educ 2019;34:116-23.
4.	Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2018;68:394-424.
5.	Rutkowska M, Hnitecka S, Nahajowski M, Dominiak M, Gerber H. Oral cancer: The first symptoms and reasons for delaying correct diagnosis and appropriate treatment. Adv Clin Exp Med 2020;29:735-43.
6.	Hamied MA, Al-Shaikhani SM. Food and risk of oral cancer (review). Tikrit J Dent Sci 2019;7:45-54.
7.	Bradshaw PT, Siega-Riz AM, Campbell M, Weissler MC, Funkhouser WK, Olshan AF. Associations between dietary patterns and head and neck cancer: The Carolina head and neck cancer epidemiology study. Am J Epidemiol 2012;175:1225-33.
8.	Akhiwu BI, Akhiwu HO, Afolaranmi T, Chuwang N, Elugbe A, Shedrach A, et al. Characterization of high risk human papilloma virus genotypes associated with oropharyngeal cancers in a Nigerian population. Pan Afr Med J 2021;38:40.
9.	De Vito R, Lee YC, Parpinel M, Serraino D, Olshan AF, Zevallos JP, et al. Shared and study-specific dietary patterns and head and neck cancer risk in an international consortium. Epidemiology 2019;30:93-102.
10.	Grosso G, Bella F, Godos J, Sciacca S, Del Rio D, Ray S, et al. Possible role of diet in cancer: Systematic review and multiple meta-analyses of dietary patterns, lifestyle factors, and cancer risk. Nutr Rev 2017;75:405-19.
11.	Hashemi R, Motlagh AD, Heshmat R, Esmaillzadeh A, Payab M, Yousefinia M, et al. Diet and its relationship to sarcopenia in community dwelling Iranian elderly: A cross sectional study. Nutrition 2015;31:97-104.
12.	Esmaillzadeh A, Azadbakht L. Food intake patterns may explain the high prevalence of cardiovascular risk factors among Iranian women. J Nutr 2008;138:1469-75.
13.	Patil PB, Bathi R, Chaudhari S. Prevalence of oral mucosal lesions in dental patients with tobacco smoking, chewing, and mixed habits: A cross-sectional study in South India. J Family Community Med 2013;20:130-5.
14.	Asthana S, Labani S, Kailash U, Sinha DN, Mehrotra R. Association of smokeless tobacco use and oral cancer: A systematic global review and meta-analysis. Nicotine Tob Res 2019;21:1162-71.
15.	Jiang X, Wu J, Wang J, Huang R. Tobacco and oral squamous cell carcinoma: A review of carcinogenic pathways. Tob Induc Dis 2019;17:29.
16.	Madani AH, Dikshit M, Bhaduri D, Aghamolaei T, Moosavy SH, Azarpaykan A. Interaction of alcohol use and specific types of smoking on the development of oral cancer. Int J High Risk Behav Addict 2014;3:e12120.
17.	Garavello W, Foschi R, Talamini R, La Vecchia C, Rossi M, Dal Maso L, et al. Family history and the risk of oral and pharyngeal cancer. Int J Cancer 2008;122:1827-31.
18.	Foulkes WD, Brunet JS, Kowalski LP, Narod SA, Franco EL. Family history of cancer is a risk factor for squamous cell carcinoma of the head and neck in Brazil: A case-control study. Int J Cancer 1995;63:769-73.
19.	Goldstein AM, Blot WJ, Greenberg RS, Schoenberg JB, Austin DF, Preston-Martin S, et al. Familial risk in oral and pharyngeal cancer. Eur J Cancer B Oral Oncol 1994;30B: 319-22.
20.	Wiseman M. The second World Cancer Research Fund/American Institute for Cancer Research expert report. Food, nutrition, physical activity, and the prevention of cancer: A global perspective. Proc Nutr Soc 2008;67:253-6.
21.	Auluck A, Walker BB, Hislop G, Lear SA, Schuurman N, Rosin M. Socio-economic deprivation: A significant determinant affecting stage of oral cancer diagnosis and survival. BMC Cancer 2016;16:569.
22.	Johnson S, McDonald JT, Corsten M, Rourke R. Socio-economic status and head and neck cancer incidence in Canada: A case-control study. Oral Oncol 2010;46:200-3.
23.	Greenberg RS, Haber MJ, Clark WS, Brockman JE, Liff JM, Schoenberg JB, et al. The relation of socioeconomic status to oral and pharyngeal cancer. Epidemiology 1991;2:194-200.
24.	Lonn E, Bosch J, Yusuf S, Sheridan P, Pogue J, Arnold JM, et al. Effects of long-term vitamin E supplementation on cardiovascular events and cancer: A randomized controlled trial. JAMA 2005;293:1338-47.
25.	Barone J, Taioli E, Hebert JR, Wynder EL. Vitamin supplement use and risk for oral and esophageal cancer. Nutr Cancer 1992;18:31-41.
26.	Gaziano JM, Sesso HD, Christen WG, Bubes V, Smith JP, MacFadyen J, et al. Multivitamins in the prevention of cancer in men: The Physicians' Health Study II randomized controlled trial. JAMA 2012;308:1871-80.
27.	Miranda J, Monteiro L, Albuquerque R, Pacheco JJ, Khan Z, Lopez-Lopez J, et al. Coffee is protective against oral and pharyngeal cancer: A systematic review and meta-analysis. Med Oral Patol Oral Cir Bucal 2017;22:e554-61.
28.	Notani PN, Jayant K. Role of diet in upper aerodigestive tract cancers. Nutr Cancer 1987;10:103-13.
29.	Islami F, Pourshams A, Nasrollahzadeh D, Kamangar F, Fahimi S, Shakeri R, et al. Tea drinking habits and oesophageal cancer in a high risk area in northern Iran: Population based case-control study. BMJ 2009;338:b929.
30.	Chazelas E, Srour B, Desmetz E, Kesse-Guyot E, Julia C, Deschamps V, et al. Sugary drink consumption and risk of cancer: Results from NutriNet-Santé prospective cohort. BMJ 2019;366:l2408.
31.	Battino M, Forbes-Hernández TY, Gasparrini M, Afrin S, Cianciosi D, Zhang J, et al. Relevance of functional foods in the Mediterranean diet: The role of olive oil, berries and honey in the prevention of cancer and cardiovascular diseases. Crit Rev Food Sci Nutr 2019;59:893-920.
32.	Kumar M, Nanavati R, Modi TG, Dobariya C. Oral cancer: Etiology and risk factors: A review. J Cancer Res Ther 2016;12:458-63.
33.	de Souza RG, Schincaglia RM, Pimentel GD, Mota JF. Nuts and human health outcomes: A systematic review. Nutrients 2017;9:1311.
34.	Olaya B, Moneta MV, Lara E, Miret M, Martín-María N, Moreno-Agostino D, et al. Fruit and vegetable consumption and potential moderators associated with all-cause mortality in a representative sample of Spanish older adults. Nutrients 2019;11:1794.
35.	Vieira AR, Abar L, Vingeliene S, Chan DS, Aune D, Navarro-Rosenblatt D, et al. Fruits, vegetables and lung cancer risk: A systematic review and meta-analysis. Ann Oncol 2016;27:81-96.
36.	Toporcov TN, Tavares GE, Rotundo LD, Vaccarezza GF, Biazevic MG, Brasileiro RS, et al. Do tobacco and alcohol modify protective effects of diet on oral carcinogenesis? Nutr Cancer 2012;64:1182-9.

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