Signet ring carcinoma of ampulla of vater

Authors
Ardeshir Talebi
Fareshteh Mohammadizadeh
Mohsen Hani
Marzie Bagheri
Azam Bagheri
Department of Pathology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
Abstract
Signet ring carcinoma is a common type of adenocarcinoma of stomach but its occurrence in ampulla of
Vater is extremely rare. There are only a few previous reported cases of signet ring carcinoma of ampulla
of Vater. Here we reported a 61-year-old woman with obstructive jaundice. Ultrasonography and computed
tomography (CT scan) examination showed intra- and extrahepatic bile duct dilatation. Endoscopic
examination with biopsies revealed a small-size mass in ampulla of Vater with diagnosis of signet ring
carcinoma. On consequent pancreatoduodenectomy the tumor was diagnosed as T2N0M0, stage IB. Because
of the specific site of signet ring carcinoma of ampulla of Vater, the tumor seems to present itself at an
early stage of disease. We review in the literature to suggest our idea.

Keywords

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Advanced Biomedical Research
Volume 2014, January
January 2014
Pages 1-4