Colloid milium


Department of Dermatology, Isfahan University of Medical Sciences, Isfahan, Iran


Colloid milium is a rare cutaneous condition with at least three distinct subtypes, characterized clinically by the development of yellowish translucent papules or plaques on sun-exposed skin, and histologically by the presence of colloid in the dermal papillae. In this case report, we present a man with multiple small papules on dorsum of his hands that in pathology confirmed to be colloid milium. Colloid milium is more commonly observed in fair-skin patients and remain unchanged; however our patient had dark skin type (Fitzpatrick skin type III) and lesions were increasing in summer and decreasing in winter.


1. Christie T, Joseph M, George J, Hruza G. Adult-oneset facial colloid miliun successfully treated with the long-plused Er: Yag laser. Dermatol Surg 2002;28:215-9.  Back to cited text no. 1
2. Innocenzi D, Barduagni F, Cerio R, Wolter M. UV-induced colloid milium. Clin Exp Dermatol 1993;18:347-50.  Back to cited text no. 2
3. Kobayashi H, Hashimoto K. Colloid and elastic fibre: Ultrastructural study on the histogenesis of colloid milium. J Cutan Pathol 1983;10:111-22.  Back to cited text no. 3
4. Lim C, Li M. Colloid milium arising in a non sun exposed area in an adult. Australas J Dermatol 2006;47:137-8.  Back to cited text no. 4
5. Hashimoto K, Miller F, Bereston ES. Colloid milium: Histochemical and electron microscopic studies. Arch Dermatol 1972;105:684-94.  Back to cited text no. 5
6. Dummer R, Laetsch B, Stutz S, Schärer L. Elastosis colloidalis conglomerate (adult colloid milium, paracolloid of the skin) a maximal manfestation of actinic elastosis. Eur J Dermatol 2006;16:163-6.  Back to cited text no. 6
7. Findlay GH, Morrison JG, Simson IW. Exogenous ochronosis and pigmented colloid milium from hydroquinone bleaching creams. Br J Dermatol 1975;93:613-22.  Back to cited text no. 7
8. Muscardin L, Bellocci M, Balus L. Papuloverrucous colloid milium: An occupational variant. Br J Dermatol 2000;143:884-7.  Back to cited text no. 8
9. Handfield-Jones SE, Atherton D, Black M. Juvenile colloid milium. Br J Dermatol 1991;125:80-1.  Back to cited text no. 9
10. Chowdhury M, Blackford S, Williams S. Juvenile colloid milium. Br J Dermatol 1999;141:102-7.  Back to cited text no. 10
11. Hashimoto K, Kumakiri M. Colloid-amyloid bodies in PUVA-treated human psoriatic patients. J Invest Dermatol 1979;72:70-80.  Back to cited text no. 11
12. Muzaffa W, Dar NR, Malik AM. Colloid milium of the upper eyelid margins. Ophthalmology 2002;109:1944-6.  Back to cited text no. 12
13. Hashimoto K, Black M. Colloid milium: A final degeneration product of actinic elastoid. J Cutan Pathol 1985;12:147-56.  Back to cited text no. 13
14. Lewis A, Le E, Quan L, Krishnan B, Schulmeier J, Hsu S. Unilateral colloid milium of the arm. J Am Acad Dermatol 2002;46:65-7.  Back to cited text no. 14
15. Apfelberg DB, Druker D, Spence B, Maser MR, Lash H. Treatment of colloid milium of the hand by dermabrasion. J Hand Surg Am 1978;3:98-100.  Back to cited text no. 15