Authors
1 Department of Biomedical Engineering, Karnataka Lingayat Education Society's College of Engineering and Technology, Belgaum, India
2 Department of Mechanical Engineering, Karnataka Lingayat Education Society's College of Engineering and Technology, Belgaum, India
3 Department of Orthopaedics, Jawaharlal Nehru Medical College, Karnataka Lingayat Education University, Belgaum, India
Abstract
Background: Fragile fractures are most likely manifestations of fatigue damage that develop under repetitive loading conditions. Numerous microcracks disperse throughout the bone with the tensile and compressive loads. In this study, tensile and compressive load tests are performed on specimens of both the genders within 19 to 83 years of age and the failure strength is estimated.
Materials and Methods: Fifty five human femur cortical samples are tested. They are divided into various age groups ranging from 19-83 years. Mechanical tests are performed on an Instron 3366 universal testing machine, according to American Society for Testing and Materials International (ASTM) standards.
Results: The results show that stress induced in the bone tissue depends on age and gender. It is observed that both tensile and compression strengths reduces as age advances. Compressive strength is more than tensile strength in both the genders.
Conclusion: The compression and tensile strength of human femur cortical bone is estimated for both male and female subjecting in the age group of 19-83 years. The fracture toughness increases till 35 years in male and 30 years in female and reduces there after. Mechanical properties of bone are age and gender dependent.
Keywords
1. | Vashishth D, Sit S. Age-related changes in bending fatigue of human cortical bone, Summer Bioengineering Conference, Florida, 2003. |
2. | Meng Y, Qin YX, Di-Masi E, Rafailovich M, Pernodet N. Bio mineralization of a self-assembled extracellular matrix for bone tissue engineering. J Tissue Eng 2009;15:355-65. |
3. | Thurner PJ, Chen CG, Ionova-Martin S, Sun L, Harman A, Porter A, et al. Osteopontin deficiency increases bone fragility but preserves bone mass. J Bone 2010;46:1564-73. |
4. | Loveridge N, Power J, Reeve J, Boyde A. Bone mineralization density and femoral neck fragility. J Bone 2004;35:929-41. |
5. | Chen QZ, Wong CT, Lu WW, Cheung KM, Leong JC, Luk KD. Strengthening mechanisms of bone bonding to crystalline hydroxyapatite in vivo. Biomaterials 2004;25:4243-54. |
6. | Rubin CD. Emerging concepts in osteoporosis and bone strength, J Med Biolog Eng 2005;21:1049-56. |
7. | Tomar V. Insights into the effects of tensile and compressive loadings on microstucture dependent fracture of trabecular bone. J Eng Fract Mech 2009;76:884-97. |
8. | Bailey AJ, Paul RG, Knott L. Mechanisms of maturation and ageing of collagen. Mech Ageing Dev 1998;106:1-56. |
9. | Bakar MS, Cheng MH, Tang SM, Yu SC. Tensile properties, tension-tension fatigue and biological response of polyetheretherketone-hydroxyapatite composites for load-bearing orthopaedic implants. J Biomaterials 2003;24:2245-50. |
10. | Nalla RK, Kruzic JJ, Kinney JH, Balooch M, Ritchie RO. Role of microstructure in the aging-related deterioration of the toughness of human cortical bone. J Mater Sci Eng 2006;26:1251-60. |
11. | Ritchie RO, Kinney JH, Kruzic JJ, Nalla RK. Cortical bone fracture, in Wiley Encyclopedia of Biomedical Engineering, 2006;32-45. |
12. | Nalla RK, Kruzic JJ, Kinney JH, Ritchie RO. Effect of aging on the toughness of human cortical bone: Evaluation by R-curves. Bone 2004;35:1240-6. |
13. | Gray RJ, Korbacher G. Compressive fatigue behaviour of bovine compact bone. J Biomech 1974;7:287-92. |
14. | Winwood K, Zioupos P, Currey JD, Cotton JR, Taylor M. The importance of the elastic and plastic components of strain in tensile and compressive fatigue of human cortical bone in relation to orthopaedic biomechanics. J Musculoskelet Neuronal Interact 2006;6:134-41. |
15. | Novitskaya E, Chen PY, Hamed E, Li J, Lubarda VA, Jasiuk I, et al. Recent advances on the measurement and calculation of the elastic moduli of cortical and trabecular bone: A review. J Theoret Appl Mech 2011;38:209-97. |
16. | Kotha SP, Guzelsu N. Tensile damage and its effects on cortical bone. J Biomech 2003;36:1683-9. |
17. | Rho JY, Zioupos P, Curry JD, Pharr GM. Microstructural elasticity and regional heterogeneity in human femoral bone of various ages examined by nano-indentation. J Biomech 2002;35:189-98. |
18. | Kotha SP, Guzelsu N. Modeling the tensile mechanical behaviour of bone along the longitudinal direction. J Theor Biol 2002;219:269-79. |
19. | Gupta HS, Zioupos P. Fracture of bone tissue: The how's and the why's. J Med Eng Phys 2008;30:1209-26. |
20. | Hoffler CE, Moore KE, Kozloff K, Zysset PK, Goldstein SA. Age, Gender, and Bone Lamellae Elastic Moduli. J Orthop Res 2000;18:432-7. |
21. | Luo G, Kaufman JJ, Chiabrera A, Bianco B, Kinney JH, Haupt D, et al. Computational methods for ultrasonic bone assessment. Ultrasound Med Biol 1999;25:823-30. |
22. | George WT, Vashishth D. Susceptibility of aging human bone to mixed-mode fracture increases bone fragility. Bone 2006;38:105-11. |