Recurrent suicide attempt and female hormones

Authors
Seyed Ghafur Mousavi 1
Shima Bateni 2
Mohammad Reza Maracy 3
Farahnaz Mardanian 4
Seyedeh Hakimeh Mousavi 2
1 Department of Psychiatry, Behavioral Sciences Reseach Center, Isfahan University of Medical Sciences, Isfahan, Iran
2 Behavioral Sciences Reseach Center, Isfahan University of Medical Sciences, Isfahan, Iran
3 Department of Epidemiology and Statistics, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran
4 Department of Obstetrics and Gynecology, Isfahan University of Medical Sciences, Isfahan, Iran
Abstract
Background: Because of more frequency of suicidal attempts in females, we need to study about its relationship with the female hormones. The aim of this study was to evaluate the serum estrogen and progesterone concentration and their relationship with suicidal attempt ranking in the attempted females.
Materials and Methods: The studied cases chose from patients who had referred to clinical toxicology emergency of Noor Hospital (Isfahan, Iran), during 2012, because of suicidal attempt. The estrogen and progesterone serum level of the 111 females were measured during 24 hours after suicidal attempt. The rank of their suicide, the demographic properties, and the menstrual cycle phase of them were also registered, as the patient's statement. The results were analyzed by ANCOVA and Kruscal-Wallis under SPSS16.
Results: Mean serum concentration of the estrogen was 76.8 pg/mL, and the mean serum concentration of progesterone was 2.99 ng/mL. Of them, 62.2% were in the luteal phase, and 37.8% were in the follicular phase, as they said. The serum progesterone concentration of the patients with more than two times suicidal attempts was significantly higher than the others.
Conclusion: The suicidal attempt ranks significantly related to the serum progesterone concentration and the luteal phase.

Keywords

1. Pallis DJ, Holding TA. The menstrual cycle and suicidal intent. J Biosoc Sci 1976;8:27-33.  Back to cited text no. 1
    
2. Dorga TD, Anderson AA, Kareday F. Menstrual cycle and suicide. Psycho Rep 2007;707:430-4.  Back to cited text no. 2
    
3. Bourgeis M, Shan P, Powl J. Incidence des period et syndrome pre ouperimenstrual study compartment suicide. Ann Med Psycho 1997;145:429-38.  Back to cited text no. 3
    
4. Baca-García E, Diaz-Sastre C, Ceverino A, Saiz-Ruiz J, Diaz FJ, de Leon J. Association between the menses and suicide attempts: A replication study. Psychosom Med 2003;65:237-44.  Back to cited text no. 4
    
5. Sein AJ, Chodorowski Z, Ciechanowicz R, Wisniewski M, Pankiewicz P. The relationship between suicidal attempts and menstrual cycle in women. Przegl Lek 2005;62:431-3.  Back to cited text no. 5
    
6. Zayas LH. A Retrospective on "The Suicidal Fit" in Mainland Puerto Ricans: Research Issues. Hisp J Behav Sci 1989;11:46-57.  Back to cited text no. 6
    
7. Targum SD, Caputo KP, Ball SK. Menstrual cycle phase and psychiatric admissions. J Affect Disord 1991;22:49-53.  Back to cited text no. 7
    
8. Baca-García E, Díaz-Sastre C, de Leon J, Saiz-Ruiz J. The relationship between menstrual cycle phases and suicide attempts. Psychosom Med 2000;62:50-60.  Back to cited text no. 8
    
9. Friedmann E, Katcher AH, Brightman VJ. A prospective study of the distribution of illness within the menstrual cycle. Motiv Emot 1978;2:355-68.  Back to cited text no. 9
    
10. Fourestié V, de Lignières B, Roudot-Thoraval F, Fulli-Lemaire I, Cremniter D, Nahoul K, et al. Suicide attempt in hypo strojenic phases of menstrual cycle. Lancet 1996;2:1357-60.  Back to cited text no. 10
    
11. Glass GS, Heninger GR, Lansky M, Talan K. Psychiatric emergency related to the menstrual cycle. Am J Psychiatry 1971;128:705-11.  Back to cited text no. 11
    
12. Tonks CM, Rose MJ. Attempted suicide and menstrual cycle. J Psychosome Res 1998;11:319-23.  Back to cited text no. 12
    
13. Tseny WS. Handbook of cultural psychiatry. San Diego, California: Academic Press; 2001.  Back to cited text no. 13
    
14. Harvard S. Psychiatric emergences. In: Sadock B, Sadock V, editors. Comprehensive textbook of psychiatry. 8 th ed. Philadelphia: Lippincott Williams and Wilkins; 2005.  Back to cited text no. 14
    
15. Fourestie V, de LB, Roudot-Thoraval F, Fulli-Lemaire I, Cremniter D, Nahoul K, et al. Suicide attempts in hypo-oestrogenic phases of the menstrual cycle. Lancet 1986;2:1357-60.  Back to cited text no. 15
    
16. Baca-Garcia E, Diaz-Sastre C, Ceverino A, García Resa E, Oquendo MA, Saiz-Ruiz J, et al. Premenstrual symptoms and luteal suicide attempts. Eur Arch Psychiatry Clin Neurosci 2004;254:326-9.  Back to cited text no. 16
    
17. Caykoylu A, Capoglu I, Ozturk I. The possible factors affecting suicide attempts in the different phases of the menstrual cycle. Psychiatry Clin Neurosci 2004;58:460-4.  Back to cited text no. 17
    
18. Baca G, Sanchez A, Gonzalez D. Menstrual cycle and profile of suicidal behavior. Acta Psychiatr Scand 1998;97:33-5.  Back to cited text no. 18
    
19. Luggin R, Tal B, Peterson B. Acute psychiatry admission related to the menstrual cycle. Acta Psychiatr Scand 1994;69:461-5.  Back to cited text no. 19
    
20. Ekeberg O, Jacobsen D. Self-poisoning and the menstrual cycle. Acta Psychiatr Scand 1986;73:239-41.  Back to cited text no. 20
    
21. Mousavi SGh, Koocheky A, Bateni V, Mardanian M. The relationship of suicide attempt and different phases of menstrual cycle in women referred to Isfahan Emergency Poisoning Center. J Res Behav Sci 2008;1:51-6.  Back to cited text no. 21
    
22. Sadock BJ, Sadock VA, Reiz P. Kapaln and Sadocks Comprehensive text book of psychiatry. 9 th ed. Philadelphia: Lippincott Williams and Wilkins; 2009.  Back to cited text no. 22
Advanced Biomedical Research
Volume 2014, september
September 2014
Pages 1-4