Percutaneous nephrolithotomy: Effect of unilateral procedure on contralateral kidney function

Authors
Mehrdad Mohammadi Sichani
Amir Behnamfar
Mohammad Hatef Khorami
Kia Nourimahdavi
Farshid Alizadeh
Mohammad Hossein Izadpanahi
Department of Urology, Isfahan University of Medical Sciences, Isfahan, Iran
Abstract
Background: Although long-term effects of percutaneous nephrolithotomy (PCNL) on renal function and structure have been evaluated, knowledge regarding the immediate effects of surgery on renal function is limited. We conducted this study to evaluate the impact of unilateral PCNL on bilateral renal function during immediate post-operative period.
Materials and Methods: From April to September 2012, 40 eligible patients were enrolled in this study and underwent unilateral PCNL. During the post-operative period, creatinine clearances (CrCl) of treated and untreated sides were estimated separately and pattern of changes in bilateral renal function following this procedure was evaluated.
Results: Following the operation, CrCl of both kidneys showed a similar pattern of changes, of course more dramatic on treated side. We observed progressive decline in CrCl of both sides followed by bilateral improvement in renal function toward pre-operative values.
Conclusions: During the early post-operative period following unilateral PCNL, both kidneys experienced a temporary drop in function warranting more intensive post-operative care.

Keywords

1.
Handa RK, Matlaga BR, Connors BA, Ying J, Paterson RF, Kuo RL, et al. Acute effects of percutaneous tract dilation on renal function and structure. J Endourol 2006;20:1030-40.  Back to cited text no. 1
    
2.
Nouralizadeh A, Sichani MM, Kashi AH. Impacts of percutaneous nephrolithotomy on the estimated glomerular filtration rate during the first few days after surgery. Urol Res 2011;39:129-33.  Back to cited text no. 2
    
3.
Dawaba MS, Shokeir AA, Hafez A, Shoma AM, El-Sherbiny MT, Mokhtar A, et al. Percutaneous nephrolithotomy in children: Early and late anatomical and functional results. J Urol 2004;172:1078-81.  Back to cited text no. 3
    
4.
Chatham JR, Dykes TE, Kennon WG, Schwartz BF. Effect of percutaneous nephrolithotomy on differential renal function as measured by mercaptoacetyl triglycine nuclear renography. Urology 2002;59:522-5.  Back to cited text no. 4
    
5.
Moskovitz B, Halachmi S, Sopov V, Burbara J, Horev N, Groshar D, et al. Effect of percutaneous nephrolithotripsy on renal function: Assessment with quantitative SPECT of (99m) Tc-DMSA renal scintigraphy. J Endourol 2006;20:102-6.  Back to cited text no. 5
    
6.
Wadhwa P, Aron M, Bal CS, Dhanpatty B, Gupta NP. Critical prospective appraisal of renal morphology and function in children undergoing shockwave lithotripsy and percutaneous nephrolithotomy. J Endourol 2007;21:961-6.  Back to cited text no. 6
    
7.
Nazaroglu H, Akay AF, Bükte Y, Sahin H, Akkus Z, Bilici A. Effects of extracorporeal shock-wave lithotripsy on intrarenal resistive index. Scand J Urol Nephrol 2003;37:408-12.  Back to cited text no. 7
    
8.
DiBona GF, Kopp UC. Neural control of renal function. Physiol Rev 1997;77:75-197.  Back to cited text no. 8
    
9.
Connors BA, Evan AP, Willis LR, Simon JR, Fineberg NS, Lifshitz DA, et al. Renal nerves mediate changes in contralateral renal blood flow after extracorporeal shockwave lithotripsy. Nephron Physiol 2003;95:p67-75.  Back to cited text no. 9
    
10.
Atici S, Zeren S, Ariboðan A. Hormonal and hemodynamic changes during percutaneous nephrolithotomy. Int Urol Nephrol 2001;32:311-4.  Back to cited text no. 10
    
11.
Unsal A, Koca G, Reºorlu B, Bayindir M, Korkmaz M. Effect of percutaneous nephrolithotomy and tract dilatation methods on renal function: Assessment by quantitative single-photon emission computed tomography of technetium-99m-dimercaptosuccinic acid uptake by the kidneys. J Endourol 2010;24:1497-502.  Back to cited text no. 11
    
12.
Handa RK, Evan AP, Willis LR, Johnson CD, Connors BA, Gao S, et al. Renal functional effects of multiple-tract percutaneous access. J Endourol 2009;23:1951-6.  Back to cited text no. 12
    
13.
Holman E, Salah MA, Tóth C. Comparison of 150 simultaneous bilateral and 300 unilateral percutaneous nephrolithotomies. J Endourol 2002;16:33-6.  Back to cited text no. 13
    
14.
Handa RK, Johnson CD, Connors BA, Gao S, Evan AP, Miller NL, et al. Renal functional effects of simultaneous bilateral single-tract percutaneous access in pigs. BJU Int 2010;105:125-8.  Back to cited text no. 14
    
15.
Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D. A more accurate method to estimate glomerular filtration rate from serum creatinine: A new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med 1999;130:461-70.  Back to cited text no. 15
Advanced Biomedical Research
Volume 2014, November
November 2014
Pages 1-5