Effect of music during general anesthesia on anesthetic consumption during vitrectomy surgery

Authors

1 Department of Anesthesiology, School of Medicine, Anesthesiology Research Center, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

2 Ophthalmology and Vision Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Abstract

Background: Controversy remains about the positive role of music during general anesthesia and postoperative recovery. We, therefore, tested the hypothesis that intraoperative exposure to classical music reduces the propofol necessary to maintain the bispectral index (BIS) close to 50 during vitrectomy surgery.
Materials and Methods: This double-blind clinical study is evaluating 50 patients undergoing vitrectomy surgery under general anesthesia. Patients were randomly assigned to music and white noise groups, and relevant sounds were played to patients after induction of anesthesia. The two groups were compared for the use of propofol as an anesthetic to maintain a BIS near 50 and for postoperative pain, anxiety, nausea, and vomiting.
Results: Propofol consumption to maintain the set BIS score was much lower in the music group than in the white noise group (78.72 ± 25.76 microgram/kg/min and 117.91 ± 36.78 microgram/kg/min, respectively, P-value = 0.000). Postoperative pain scores were also much lower in the music group than in the white noise group (P-value = 0.000) and anxiety levels between these two groups did not differ (P-value = 0.870). No patient in the music group had complaints of postoperative nausea and vomiting (PONV) compared to six patients in the white noise group (P-value = 0.011).
Conclusions: Listening to music during general anesthesia for vitrectomy surgery can reduce the use of anesthetics, postoperative pain, and PONV. Further, controlled studies are necessary to confirm our results.

Keywords

1.
Maranets I, Kain ZN. Preoperative anxiety and intraoperative anesthetic requirements. Anesth Analg 1999;89:1346.  Back to cited text no. 1
    
2.
Kain ZN, Sevarino F, Alexander GM, Pincus S, Mayes LC. Preoperative anxiety and postoperative pain in women undergoing hysterectomy. A repeated-measures design. J Psychosom Res 2000;49:417-22.  Back to cited text no. 2
    
3.
Bradt J, Dileo C, Shim M. Music interventions for preoperative anxiety. Cochrane Database Syst Rev 2013;6:CD006908.  Back to cited text no. 3
    
4.
Licina A, Sidhu S, Xie J, Wan C. Local versus general anaesthesia for adults undergoing pars plana vitrectomy surgery. Cochrane Database Syst Rev 2016;9:CD009936.  Back to cited text no. 4
    
5.
Palmer JB, Lane D, Mayo D, Schluchter M, Leeming R. Effects of music therapy on anesthesia requirements and anxiety in women undergoing ambulatory breast surgery for cancer diagnosis and treatment: A randomized controlled trial. J Clin Oncol 2015;33:3162-8.  Back to cited text no. 5
    
6.
Masuda T, Miyamoto K, Shimizu K. Effects of music listening on elderly orthopaedic patients during postoperative bed rest. http://dx.doi.org/101080/08098130509478121 [Internet]. 2009;14:4-14. Available from: https://www.tandfonline.com/doi/abs/100.1080/08098130509478121. [Last accessed on 2022 Dec 01].  Back to cited text no. 6
    
7.
Martin-Saavedra JS, Ruiz-Sternberg AM. The effects of music listening on the management of pain in primary dysmenorrhea: A randomized controlled clinical trial. https://doi.org/101080/0809813120201761867 [Internet]. 2020 Oct 19 [cited 2022 Dec 1];29(5):398–415. Available from: https://www.tandfonline.com/doi/abs/100.1080/08098131.2020.1761867.  Back to cited text no. 7
    
8.
Dowd NP, Cheng DC, Karski JM, Wong DT, Munro JA, Sandler AN. Intraoperative awareness in fast-track cardiac anesthesia. Anesthesiology 1998;89:1068-73.  Back to cited text no. 8
    
9.
Bonebakker AE, Jelicic M, Passchier J, Bonke B. Memory during general anesthesia: Practical and methodological aspects. Conscious Cogn 1996;5:542-61.  Back to cited text no. 9
    
10.
Riker RR, Fraser GL, Simmons LE, Wilkins ML. Validating the sedation-agitation scale with the bispectral index and visual analog scale in adult ICU patients after cardiac surgery. Intensive Care Med 2001;27:853-8.  Back to cited text no. 10
    
11.
Ilkkaya NK, Ustun FE, Sener EB, Kaya C, Ustun YB, Koksal E, et al. The effects of music, white noise, and ambient noise on sedation and anxiety in patients under spinal anesthesia during surgery. J Perianesth Nurs 2014;29:418-26.  Back to cited text no. 11
    
12.
do Amaral MAS, Neto MG, de Queiroz JG, Martins-Filho PRS, Saquetto MB, Oliveira Carvalho V. Effect of music therapy on blood pressure of individuals with hypertension: A systematic review and Meta-analysis. Int J Cardiol 2016;214:461-4.  Back to cited text no. 12
    
13.
Son SM, Kwag SW. Effects of white noise in walking on walking time, state anxiety, and fear of falling among the elderly with mild dementia. Brain Behav 2020;10:e01874.  Back to cited text no. 13
    
14.
Kuan G, Morris T, Terry P. Effects of music on arousal during imagery in elite shooters: A pilot study. PLoS One 2017;12:e0175022.  Back to cited text no. 14
    
15.
Riker RR, Fraser GL. Monitoring sedation, agitation, analgesia, neuromuscular blockade, and delirium in adult ICU patients. Semin Respir Crit Care Med 2001;22:189-98.  Back to cited text no. 15
    
16.
Cepeda MS, Diaz JE, Hernandez V, Daza E, Carr DB. Music does not reduce alfentanil requirement during patient-controlled analgesia (PCA) use in extracorporeal shock wave lithotripsy for renal stones. J Pain Symptom Manage 1998;16:382-7.  Back to cited text no. 16
    
17.
Matsota P, Christodoulopoulou T, Smyrnioti ME, Pandazi A, Kanellopoulos I, Koursoumi E, et al. Music's use for anesthesia and analgesia. J Altern Complement Med 2013;19:298-307.  Back to cited text no. 17
    
18.
Mirbagher Ajorpaz N, Aghajani M, Shahshahani M. The effects of music and Holy Quran on patient's anxiety and vital signs before abdominal surgery. Evidence Based Care 2011;1:63-76.  Back to cited text no. 18
    
19.
Koch ME, Kain ZN, Ayoub C, Rosenbaum SH. The sedative and analgesic sparing effect of music. Anesthesiology 1998;89:300-6.  Back to cited text no. 19
    
20.
Al-Jubouri MBA, Isam SR, Hussein SM, Machuca-Contreras F. Recitation of quran and music to reduce chemotherapy-induced anxiety among adult patients with cancer: A clinical trial. Nurs Open 2021;8:1606-14.  Back to cited text no. 20
    
21.
Binns-Turner PG, Wilson LL, Pryor ER, Boyd GL, Prickett CA. Perioperative music and its effects on anxiety, hemodynamics, and pain in women undergoing mastectomy. AANA J 2011;79 (4 Suppl):S21-7.  Back to cited text no. 21
    
22.
Kahloul M, Mhamdi S, Nakhli MS, Sfeyhi AN, Azzaza M, Chaouch A, et al. Effects of music therapy under general anesthesia in patients undergoing abdominal surgery. Libyan J Med 2017;12:1260886.  Back to cited text no. 22
    
23.
Choi S, Park SG, Bellan L, Lee HH, Chung SK. Crossover clinical trial of pain relief in cataract surgery. Int Ophthalmol 2018;38:1027-33.  Back to cited text no. 23
    
24.
Ikedo F, Gangahar DM, Quader MA, Smith LM. The effects of prayer, relaxation technique during general anesthesia on recovery outcomes following cardiac surgery. Complement Ther Clin Pract 2007;13:85-94.  Back to cited text no. 24
    
25.
Reza N, Ali SM, Saeed K, Abul-Qasim A, Reza TH. The impact of music on postoperative pain and anxiety following cesarean section. Middle East J Anaesthesiol 2007;19:573-86.  Back to cited text no. 25
    
26.
Szmuk P, Aroyo N, Ezri T, Muzikant G, Weisenberg M, Sessler DI. Listening to music during anesthesia does not reduce the sevoflurane concentration needed to maintain a constant bispectral index. Anesth Analg 2008;107:77-80.  Back to cited text no. 26
    
27.
Nilsson U, Rawal N, Unestهhl LE, Zetterberg C, Unosson M. Improved recovery after music and therapeutic suggestions during general anaesthesia: A double-blind randomised controlled trial. Acta Anaesthesiol Scand 2001;45:812-7.  Back to cited text no. 27
    
28.
Whitaker MH. Sounds soothing: Music therapy for postoperative pain. Nursing 2010;40:53-4.  Back to cited text no. 28
    
29.
Schneider MA. The effect of listening to music on postoperative pain in adult orthopedic patients. J Holist Nurs 2018;36:23-32.  Back to cited text no. 29