The evaluation of mood condition among depressed adolescent students in Isfahan after 6 years

Authors

1 Department of Psychiatry, School of Medicine, Behavioral Sciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

2 Department of Biostatistics, School of Public Health, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background: This study has carried out to find the recovery rate, depression recurrence, changing of diagnose into bipolar mood disorder (BMD) and appearing other psychiatric disorders including obsessive compulsive disorder, oppositional defiant disorder (ODD), substance induced disorders, attention deficit and hyperactivity disorder, and anxiety disorders after 6 years among students having major depression disorder in Isfahan and its relation to some demographic factors.
Materials and Methods: In this historical cohort study, 278 students studying in guidance school, in 2006 being 11–16-year-old and were diagnosed to have major depressive disorder participated. Data collection was done by completing children depression on inventory, Young Maria Rating Scale and also final diagnosis determination through interview by psychiatrists. To analyze the data, in addition to use descriptive statistics, multinomial and multiple logistic regressions were used to evaluate the relationships. All the analyses were done using SPSS 20.




Results: About 34.9 of adolescents have suffered from depression after 6 years. Depression in 12.2% has been changed into BMD. The BMD morbidity chance was less in girls rather than depression one. The ratio of drug abuse in girls was less than boys (odds ratio [OR] = 0.471, P = 0.046). Students received no treatment or only pharmacotherapy, were more caught by ODD in comparison with those cases who received both pharmacotherapy and psychotherapy (P = 0.005, 0.038 and OR = 4.29 and 5.88).
Conclusion: About half of students after 6 years are caught by depression or BMD. It reveals the importance of this disorder and its role in making behavioral problems for adolescents in their future.

Keywords

1.
Harrington R, Bredenkamp D, Groothues C, Rutter M, Fudge H, Pickles A. Adult outcomes of childhood and adolescent depression. III. Links with suicidal behaviours. J Child Psychol Psychiatry 1994;35:1309-19.  Back to cited text no. 1
    
2.
Fleming JE, Offered DR. Epidemiology of adolescents' depression disorder: A critical review. J Am Acad Child Adolesc Psychiatry 2002;69:581-92.  Back to cited text no. 2
    
3.
Ihle W, Esser G, Laucht M, Schmidt MH. Prevalence, course, and risk factors of depressive disorders. Bundesgesundheitsblatt (Article in German) 2004;47:782-35.  Back to cited text no. 3
    
4.
Kilpatrick DG, Ruggiero KJ, Acierno R, Saunders BE, Resnick HS, Best CL. Violence and risk of PTSD, major depression, substance abuse/dependence, and comorbidity: Results from the National Survey of Adolescents. J Consult Clin Psychol 2003;71:692-700.  Back to cited text no. 4
    
5.
Wagner KD, Brent DA. Depressive disorders and suicide. In: Sadock BJ, Sadock VA, Ruiz P, editors. Kaplan and Sadock's Comprehensive Textbook of Psychiatry. 9th ed. Philadelphia: Lippincott Williams and Wilkins; 2009. p. 3652-63.  Back to cited text no. 5
    
6.
Freres DR, Gillham JE, Reivich K, Shatté AJ. Preventing depressive symptoms in middle school students: The Penn Resiliency Program. Int J Emerg Ment Health 2002;4:31-40.  Back to cited text no. 6
    
7.
Thombs BD, Roseman M, Kloda LA. Depression screening and mental health outcomes in children and adolescents: A systematic review protocol. Syst Rev 2012;1:58.  Back to cited text no. 7
    
8.
Aalto-Setala T, Marttunen M, Tuulio-Henriksson A, Poikolainen K, Lonnqvist J. Depressive symptoms in adolescence as predictors of early adulthood depressive disorders and maladjustment. Evid Based Ment Health 2003;6:60.  Back to cited text no. 8
    
9.
Dilsaver SC, Akiskal HS. Preschool-onset mania: Incidence, phenomenology and family history. J Affect Disord 2004;82 Suppl 1:S35-43.  Back to cited text no. 9
    
10.
Weller EB, Weller RA. Depression in adolescents growing pains or true morbidity? J Affect Disord 2000;61 Suppl 1:9-13.  Back to cited text no. 10
    
11.
Shakibaei F, Izadi M. Epidemiologic evaluation of depression among high school students in Isfahan in 2007. Research project. Isfahan, Iran: Isfahan University of Medical Sciences; 2008.  Back to cited text no. 11
    
12.
Angst J. Comorbidity of anxiety, phobia, compulsion and depression. Int Clin Psychopharmacol 2012;8 Suppl 1:21-5.  Back to cited text no. 12
    
13.
Harrington RC. Depressive disorder in children and adolescents. Br J Hosp Med 1990;43:108-12.  Back to cited text no. 13
    
14.
Pélissolo A, André C, Chignon JM, Dutoit D, Martin P, Richard-Berthe C, et al. Anxiety disorders in private practice psychiatric out-patients: Prevalence, comorbidity and burden (DELTA study). Encephale 2002;28:510-9.  Back to cited text no. 14
    
15.
Lewinsohn PM, Clarke GN, Seeley JR, Rohde P. Major depression in community adolescents: Age at onset, episode duration, and time to recurrence. J Am Acad Child Adolesc Psychiatry 1994;33:809-18.  Back to cited text no. 15
    
16.
Emslie GJ, Rush AJ, Weinberg WA, Gullion CM, Rintelmann J, Hughes CW. Recurrence of major depressive disorder in hospitalized children and adolescents. J Am Acad Child Adolesc Psychiatry 1997;36:785-92.  Back to cited text no. 16
    
17.
Kovacs M, Gatsonis C, Paulauskas SL, Richards C. Depressive disorders in childhood. IV. A longitudinal study of comorbidity with and risk for anxiety disorders. Arch Gen Psychiatry 1989;46:776-82.  Back to cited text no. 17
    
18.
Essau CA. Course and outcome of major depressive disorder in non-referred adolescents. J Affect Disord 2007;99:191-201.  Back to cited text no. 18
    
19.
Rhebergen D, Batelaan NM, de Graaf R, Nolen WA, Spijker J, Beekman AT, et al. The 7-year course of depression and anxiety in the general population. Acta Psychiatr Scand 2011;123:297-306.  Back to cited text no. 19
    
20.
Jonsson U, Bohman H, von Knorring L, Olsson G, Paaren A, von Knorring AL. Mental health outcome of long-term and episodic adolescent depression: 15-year follow-up of a community sample. J Affect Disord 2011;130:395-404.  Back to cited text no. 20
    
21.
Birmaher B, Arbelaez C, Brent D. Course and outcome of child and adolescent major depressive disorder. Child Adolesc Psychiatr Clin N Am 2002;11:619-37, x.  Back to cited text no. 21
    
22.
Soltanifar A, Bina M. Depressive symptomatology in school children of Tehran-Iran (9-11 years old) and its relation to function of their families. Q J Fundam Ment Health 2007;9:7-14.  Back to cited text no. 22
    
23.
Sooky Z, Sharifi KH, Tagharrobi Z, Akbari H, Mesdaghinia A. Depression prevalence and its correlation with the psychosocial need satisfaction among Kashan high-school female students. Feyz J Kashan Univ Med Sci Autumn 2010;14:256-63.  Back to cited text no. 23
    
24.
Zarrabi H, Koosha M, Mohtasham Amiri Z, Kiani SA. Prevalence of psychopathology in high school students in Rasht. J Guilan Univ Med Sci 2001;10:39-40, 50-5.  Back to cited text no. 24
    
25.
Nadkarni RB, Fristad MA. Clinical course of children with a depressive spectrum disorder and transient manic symptoms. Bipolar Disord 2010;12:494-503.  Back to cited text no. 25
    
26.
Molavi P, Shahrivar Z, Garaee JM. Six-month outcome predictor factors of manic and mixed bipolar disorders of children and adolescents admitted in Tehran Rozbeh hospital. J Ardebil Univ Med Sci 2011;13:269-81.  Back to cited text no. 26
    
27.
Molavi P, Shahrivar Z, Gharaee JM, Basharpoor S, Sharghi A, Nikparvar F. Short-time outcome predictors of bipolar disorder type I in children and adolescents. Iran J Psychiatry Clin Psychol 2012;18:128-37.  Back to cited text no. 27
    
28.
Aghaei A, Isfahani MR, Nikyar H, Mehdizadehgan I. A comparison of three methods of drug, cognitive and behavior therapy in reducing depression among adolescents. Knowledge Research in Applied Psychology. 2007;29:69-80. [Persian]  Back to cited text no. 28
    
29.
Habibi M, Besharat MA, Bahrami-Ehsan H, Rostami R, Ferrer-Wreder L. Predicting substance use in adolescents based on risk indices and individual protective preventing, family, peers and location. J Clin Psychol 2012;4:43-54.  Back to cited text no. 29