Advanced Biomedical Research
Adverse effects of BCG vaccine 1173 P2 in Iran: A meta-analysis
Authors
- Saied Mostaan 1
- Bahador Yazdanpanah 2
- Rasool Moukhah 2
- Hamid Reza Hozouri 2
- Manouchehr Rostami 2
- Mohsen Khorashadizadeh 3
- Javad Zerehsaz 4
- Ramin Pirhajati Mahabadi 4
- Arya Saadi 5
- Hossein Khanahmad 6
- Mohammad Pooya 1
1 Department of Molecular Biology, Pasteur Institute of Iran, Tehran, Iran
2 Department of BCG, Production and Research Complex, Pasteur Institute of Iran, Tehran, Iran
3 Department of Cellular and Molecular Biology, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran
4 Department of Bacteriology, Medical School, Tarbiat Modarres University, Tehran, Iran
5 Technical Office, Pasteur Institute of Iran, Tehran, Iran
6 Isfahan University of Medical Sciences, Isfahan, Iran
Abstract
Although in the last two decades the World Health Organization (WHO) has introduced tuberculosis as “a threat to global”, the vaccination with the Mycobacterium bovis Bacillus Calmette-Guerin (BCG) is the only way for the prevention of this fatal infectious disease. Despite of the efficacy of BCG vaccine especially against infants' meningitis, it has still some limitations due to a variety of adverse effects. Many studies have evaluated the side effects of different strains of BCG vaccines in different countries. In Iran, some studies have been done so far to evaluate the adverse effects of 1173 P2 strain which is used for BCG vaccination. Each of these studies have used different standardization and sampling methods. This review will survey all studies that have been published about adverse effects of 1173 P2 strain of BCG vaccine in Iran using data mining methods.
Keywords
| 1. |
World Health Organization (2006). TB country profile/Iran.  |
| 2. |
Hestvik AL, Hmama Z, Av-Gay Y. Mycobacterial manipulation of the hostcell. FEMS Microbiol Rev 2005;29:1041-50. |
| 3. |
Rook GA, Seah G, Ustianowski A. M.tuberculosis: Immunobiology and vaccination. Eur Respir J 2001;17:537-57. |
| 4. |
Behr MA. BCG—different strains, different vaccines? Lancet Infect Dis 2002;2:86-92. |
| 5. |
Weill-Halle B, Turpin R. Premiers essays de vaccination antituberculeuse del'enfant parle Bacille Ca;mette-Guerin(BCG). Bull Mem Soc Med Hosp de Paris 1925;49:1589-601. |
| 6. |
AfsharPaiman S, Siadati A, Mamishi S, Tabatabaie P, Khotaee G. Disseminated Mycobacteriumbovis iInfection after BCG vaccination. Iran J Allergy Asthma Immunol 2006;5:133-7. |
| 7. |
Karimi A, Nateghian A, Mamishi S. 8 case report of disseminated BCG during 1998-2002 in Tehran Pediatric Center. Maz Uni Med Sci 2003;13:38. |
| 8. |
Seyfhashemi M, Hemati A, Mazaheri M, Azarbarin A, Hamedi P. Complications of BCG vaccination in children. Iran J Pediatr 2005;3:209-14. |
| 9. |
Ghoreishi FE. Case report of BCGitis affected right muscle of abdomen. J Isfahan Med School 2003;27:71:57 |
| 10. |
Mansouri D, Adimi P, Mirsaeidi M, Mansouri N, Khalilzadeh S, Masjedi MR, et al. Inherited disorders of the IL-12-IFN-γ axis in patients with disseminated BCG infection. Eur J Pediatr 2005;164:753-7. |
| 11. |
Zadie MT, Vahedi A, Ilkhanizadeh B, Norouzinia F, Ghavam F. Post BCG vaccination Xanthogranuloma. Urm Med J 2006;17138-40. |
| 12. |
Hematyar M, Chohdari A. Prevalence of BCG adenitis in infants vaccinated at birth. The Journal of Qazvin Univ Med Sci 2006;9:42-6. |
| 13. |
Alborzi A, Mostafavi N. Retropretoneal abscess due to disseminated bacilli Calmette-Guerin infection. Jpn J Infect Dis 2007;60:392-3. |
| 14. |
Ghadiri K, Afsharian M, Vaziri S, Mansouri F, Namdari S. Kordestan Univ Med Sci J 2007;12:91-6. |
| 15. |
Rezai MS, Khotaei G, Mamishi S, Kheirkhah M, Parvaneh N. Disseminated Bacillus Calmette–Guerin Infection after BCG Vaccination. J Trop Pediatr 2008;54:413-6. |
| 16. |
Behjati M, Ayatollahi J. Post BCG Lymphadenitis in Vaccinated Infants in Yazd, Iran. I J Pediatr 2008;18:351-6. |
| 17. |
Sadeghi-Shabestari M, Vesal S, Jabbarpour-Bonyadi M, de Villatay JP, Fischer A, Rezaei N. Novel RAG2 Mutation in a Patient with T– B– Severe Combined Immunodeficiency and Disseminated BCG Disease. J Investig Allergol Clin Immunol 2009;19:494-6. |
| 18. |
Movahedi Z, Norouzi S, Mamishi S, Rezaei N. BCGiosis as a presenting feature of a child with chronic granulomatous disease. Braz J Infect Dis 2011;15:83-6. |
| 19. |
Jadali F, Karimi A, Armin S, Gharib A, Fallah F, Sharifian M, et al. Detection of Disseminated Mycobactrial Infection Due to BCG Vaccination (BCGosis) in 4 Suspected Infant Autopsies by PCR Method. Iran J Pathol 2007;2:89-93. |
| 20. |
Farshchian M, Saba MS. Adenitis due to BCG vaccination. Hakim Res J 1999;22:83-7.
|
)