Upper Eyelid Silicone Oil Migration After Sutureless 23-Gauge Vitrectomy

Document Type : CASE REPORT


1 Isfahan Eye Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

2 Emam Khomeini Eye Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran

3 Vitreous-Retina-Macula Consultants of New York, 460 Park Ave, Fifth Floor, New York, NY 10022, United States

4 Eye Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran


To report a case of upper eyelid swelling and ptosis caused by silicone oil migration in a patient after sutureless 23-gauge pars plana vitrectomy and silicone oil injection. A 36-year-old female was referred to eye clinic with total retinal detachment (RD) and superotemporal giant dialysis secondary to trauma in the left eye. Transconjunctival sutureless 23-gauge pars plana vitrectomy and intraocular silicone oil (1300 centistokes) injection were performed. After about 5 months, she came back with the left upper eyelid and periorbital swelling. Palpation of the eyelid revealed soft and mobile subcutaneous small lumps that were not attached to the skin. Computed tomography scan of the orbit showed an 11 mm × 8 mm soft tissue density mass in lateral aspect of the left orbit. Transcutaneously surgical exploration was performed. The patient was seen after 1 week postoperatively and there was a significant improvement of the ptosis. Eyelid swelling and ptosis caused by silicone oil migration after RD surgery are very rare and this is one of the few reports in literature.


Gonzalez MA, Flynn HW Jr., Smiddy WE, Albini TA, Berrocal AM, Tenzel P. Giant retinal tears after prior pars plana vitrectomy: Management strategies and outcomes. Clin Ophthalmol 2013;7:1687-91.  Back to cited text no. 1
Cibis PA, Becker B, Okun E, Canaan S. The use of liquid silicone in retinal detachment surgery. Arch Ophthalmol 1962;68:590-9.  Back to cited text no. 2
Abrams GW, Azen SP, McCuen BW, Flynn HW Jr, Lai MY, Ryan SJ. Vitrectomy with silicone oil or long-acting gas in eyes with severe proliferate vitreoretinopathy: Results of Additional and long-term follow-up. Silicone Study Report 11. Arch Ophthalmol 1997;115:335-44.  Back to cited text no. 3
Light DJ. Silicone oil emulsification in the anterior chamber after vitreoretinal surgery. Optometry 2006;77:446-9.  Back to cited text no. 4
Budenz DL, Taba KE, Feuer WJ, Eliezer R, Cousins S, Henderer J, et al. Surgical management of secondary glaucoma after pars plana vitrectomy and silicone oil injection for complex retinal detachment. Ophthalmology 2001;108:1628-32.  Back to cited text no. 5
Giordano GG, Refojo MF. Silicone oils as vitreous substitutes. Prog Polymer Sci 1998;23:509-32.  Back to cited text no. 6
Garnier S, Rahmi A, Grasswil C, Kodjikian L. Three hundred and sixty degree retinotomy for retinal detachments with severe proliferative vitreoretinopathy. Graefes Arch Clin Exp Ophthalmol 2013;251:2081-5.  Back to cited text no. 7
Ichhpujani P, Jindal A, Jay Katz L. Silicone oil induced glaucoma: A review. Graefes Arch Clin Exp Ophthalmol 2009;247:1585-93.  Back to cited text no. 8
Ohira A, Wilson CA, deJuan E Jr., Murata Y, Soji T, Oshima K. Experimental retinal tolerance to emulsified silicone oil. Retina 1991;11:259-65.  Back to cited text no. 9
Papp A, Kiss EB, Tímár O, Szabó E, Berecki A, Tóth J, et al. Long-term exposure of the rabbit eye to silicone oil causes optic nerve atrophy. Brain Res Bull 2007;74:130-3.  Back to cited text no. 10
Crisp A, de Juan E Jr., Tiedeman J. Effect of silicone oil viscosity on emulsification. Arch Ophthalmol 1987;105:546-50.  Back to cited text no. 11
Quintyn JC, Genevois O, Ranty ML, Retout A. Silicone oil migration in the eyelid after vitrectomy for retinal detachment. Am J Ophthalmol 2003;136:540-2.  Back to cited text no. 12
Donker DL, Paridaens D, Mooy CM, van den Bosch WA. Blepharoptosis and upper eyelid swelling due to lipogranulomatous inflammation caused by silicone oil. Am J Ophthalmol 2005;140:934-6.  Back to cited text no. 13
Deguchi Y, Maeno T, Hori Y, Hiruta N, Sasai D, Sato Y. Migration of intraocular silicone oil from the vitreous cavity into the upper eyelid causing ptosis. Case Rep Ophthalmol 2014;5:226-30.  Back to cited text no. 14
Eckardt C. Transconjunctival sutureless 23-gauge vitrectomy. Retina 2005;25:208-11.  Back to cited text no. 15
Eller AW, Friberg TR, Mah F. Migration of silicone oil into the brain: A complication of intraocular silicone oil for retinal tamponade. Am J Ophthalmol 2000;129:685-8.  Back to cited text no. 16
Nazemi PP, Chong LP, Varma R, Burnstine MA. Migration of intraocular silicone oil into the subconjunctival space and orbit through an Ahmed glaucoma valve. Am J Ophthalmol 2001;132:929-31.  Back to cited text no. 17
Yu JT, Apte RS. A case of intravitreal silicone oil migration to the central nervous system. Retina 2005;25:791-3.  Back to cited text no. 18
Fangtian D, Rongping D, Lin Z, Weihong Y. Migration of intraocular silicone into the cerebral ventricles. Am J Ophthalmol 2005;140:156-8.  Back to cited text no. 19
Dithmar S, Schuett F, Voelcker HE, Holz FG. Delayed sequential occurrence of perfluorodecalin and silicone oil in the subretinal space following retinal detachment surgery in the presence of an optic disc pit. Arch Ophthalmol 2004;122:409-11.  Back to cited text no. 20