Background: Chronic obstructive pulmonary disease (COPD) is an increasing cause of morbidity and mortality worldwide. Anemia is seen as a common comorbidity in COPD patients associated with reduced functional capacity, impaired quality of life, greater likelihood of hospitalization, and early mortality. The aim is to study the prevalence of anemia in patients with COPD and to study its association with different parameters. Materials and Methods: In the present case–control study, 150 stable COPD patients were enrolled from the Outpatient Department of Respiratory Medicine, King George Medical University, Lucknow, from October 2015 to January 2017. GraphPad PRISM version 6.01 was used for the analysis of data. Chi-square test was used to compare between the groups. P < 0.05 was considered statistically significant. Results: The present study showed the prevalence of anemia in COPD patients to be 31.6%. The mean hemoglobin level in anemic group was 11.04 ± 1.1 g/dl, whereas in nonanemic group, it was 13.9 ± 0.8 g/dl. Anemia was significantly associated with increased dyspnea in our study which was assessed by modified Medical Research Council grade (P = 0.04). Conclusion: The prevalence of anemia in COPD patients was 31.6%. Anemia is present as comorbidity in COPD patients and is associated with poor quality of life and increased morbidity in the form of number of exacerbation and hospital admission. Identification and correction of anemia in COPD patients may improve their clinical outcome.
World Health Organization. Burden of COPD. Available from: http://www.who.int/respiratory/copd/burden/en. [Last accessed on 2017 Dec 08].
Carroz KP, Morera J. Anemia in Chronic Obstructive Pulmonary Disease. London, IntechOpen: Anemia; 2012. Dr. Donald Silverberg (Ed.), ISBN: 978-953-51-0138-3, InTech, Available from: http://www.intechopen.com/books/anemia/anemia-in-chronic-obstructive-pulmonary-disease. [Last access on 2018 Feb 02].
Global Strategy for the Diagnosis, Management and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD); 2016. Available from: http://www.goldcopd.org. [Last accessed on 2018 May 11].