Prevalence and Risk Factors of Allergic Rhinitis in Primary School Students of Isfahan, Iran

Document Type : Original Article

Authors

1 Department of Pediatrics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

2 Department of Allergy and Clinical Immunology, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background: Allergic rhinitis (AR) is one of the most common chronic diseases of childhood. Different studies have indicated an increasing prevalence of AR worldwide. The most common complaints of the patients are itching, tearing eyes, and rhinorrhea. The present study aims to assess the prevalence and risk factors of AR among 6–7-year-old children of Isfahan Province, Iran. Materials and Methods: This cross-sectional study conducted on 973 67-year-old primary school students of Isfahan Province in 2016. The study was conducted based on the International Study of Asthma and Allergies in Childhood questionnaire. Results: This study was conducted on 322 (33.1%) 6-year-old and 651 (66.9%) 7-year-old students. A total of 563 (57.9%) and 410 (42.1%) students were male and female, respectively. AR was diagnosed in 397 (40.8%) cases that 190 (47.8%) and 130 (32.7%) showed seasonal and permanent AR, respectively. A percentage of 44.7% of 6-year-old and 38.9% of 7-year-old (P = 0.04) students, 42.1% of males and 39% of females (P = 0.336), had AR; however, the percentages were not significant (P = 0.005). Exposure to smoking, plants, and domestic association with AR was not significant (P = 0.317, P = 0.863, and P = 0.253, respectively), but infancy breastfeeding association was significant (P = 0.015). Residence in the second area of Isfahan city was accompanied by higher prevalence of AR (P = 0.006). Conclusion: The prevalence of AR was considerably higher in Isfahan as one of the largest cities of Iran. It was significantly associated with age, infancy milk feeding, and area of residence but not with sex, smoking, plant, and domestic exposure.

Keywords

1.
Tamay Z, Akcay A, Ergin A, Güler N. Dietary habits and prevalence of allergic rhinitis in 6 to 7-year-old schoolchildren in Turkey. Allergol Int 2014;63:553-62.  Back to cited text no. 1
    
2.
Kliegman, Robert M, Waldo E. Nelson textbook of pediatrics e-book. Philadelphia: Elsevier Health Sciences; 2007.  Back to cited text no. 2
    
3.
Khaldi F, Fakhfakh R, Mattoussi N, Ben Ali B, Zouari S, Khémiri M. Prevalence and severity of asthma, allergic rhinoconjunctivitis and atopic eczema in “Grand tunis” school children: ISAAC. Tunis Med 2005;83:269-73.  Back to cited text no. 3
    
4.
Kao CC, Huang JL, Ou LS, See LC. The prevalence, severity and seasonal variations of asthma, rhinitis and eczema in taiwanese schoolchildren. Pediatr Allergy Immunol 2005;16:408-15.  Back to cited text no. 4
    
5.
Ghaffari J, Aarabi M. The prevalence of pediatric asthma in the Islamic Republic of Iran: A systematic review and meta-analysis. J Pediatr Rev 2013;1:2-11.  Back to cited text no. 5
    
6.
Ellwood P, Asher MI, Björkstén B, Burr M, Pearce N, Robertson CF, et al. Diet and asthma, allergic rhinoconjunctivitis and atopic eczema symptom prevalence: An ecological analysis of the international study of asthma and allergies in childhood (ISAAC) data. ISAAC phase one study group. Eur Respir J 2001;17:436-43.  Back to cited text no. 6
    
7.
Leung R, Ho P, Lam CW, Lai CK. Sensitization to inhaled allergens as a risk factor for asthma and allergic diseases in Chinese population. J Allergy Clin Immunol 1997;99:594-9.  Back to cited text no. 7
    
8.
Hatami G, Amir AE, Najafi A, Razavi S, Afrasiabi K, Afarid M, et al. Prevalence of asthma and asthma-related symptoms among 13-14yr. School children in Bushehr-ISSAC. Iranian South Medical Journal 2003;167-175  Back to cited text no. 8
    
9.
Mohammadzadeh I, Ghafari J, Barari SK, Tamadoni A, Esmaeili DM, Alizadeh NR. The prevalence of asthma, allergic rhinitis and eczema in north of Iran: The international study of asthma and allergies in childhood (ISAAC). Iranian Journal of Pediatrics 2008;117-122.  Back to cited text no. 9
    
10.
Ghaffari J, Mohammadzadeh I, Khalilian A, Rafatpanah H, Mohammadjafari H, Davoudi A, et al. Prevalence of asthma, allergic rhinitis and eczema in elementary schools in Sari (Iran). Caspian J Intern Med 2012;3:372-6.  Back to cited text no. 10
    
11.
Gharagosloo M, Khalili S, Karimi B, Honartnand M, Jafari H, Moosavi G. Asthma, allergic rhinitis and atopic eczema in schoolchildren Kashan (1998-1999). Tehran Univ Med J 2003;61:24-30.  Back to cited text no. 11
    
12.
Mohammadzadeh I, Ghafari J, Barari SR, Tamaddoni A, Esmaeili DM, Alizadeh NR. The prevalence of asthma, allergic rhinitis and eczema in North of Iran. Iranian Journal of Pediatrics 2010;20:374.  Back to cited text no. 12
    
13.
Stipić-Marković A, Pevec B, Pevec MR, Custović A. Prevalence of symptoms of asthma, allergic rhinitis, conjunctivitis and atopic eczema: ISAAC (International Study of Asthma and Allergies in Childhood) in a population of schoolchildren in Zagreb. Acta Med Croatica 2003;57:281-5.  Back to cited text no. 13
    
14.
Banac S, Tomulić KL, Ahel V, Rozmanić V, Simundić N, Zubović S, et al. Prevalence of asthma and allergic diseases in Croatian children is increasing: Survey study. Croat Med J 2004;45:721-6.  Back to cited text no. 14
    
15.
Arnedo-Pena A, García-Marcos L, García Hernández G, Aguinagua Ontoso I, González Díaz C, Morales Suárez-Varela M, et al. Time trends and geographical variations in the prevalence of symptoms of allergic rhinitis in 6-7-year-old children from eight areas of spain according to the ISAAC. An Pediatr (Barc) 2005;62:229-36.  Back to cited text no. 15
    
16.
Georgy V, Fahim HI, El-Gaafary M, Walters S. Prevalence and socioeconomic associations of asthma and allergic rhinitis in Northern [corrected] Africa. Eur Respir J 2006;28:756-62.  Back to cited text no. 16
    
17.
Asher MI, Montefort S, Björkstén B, Lai CK, Strachan DP, Weiland SK, et al. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC phases one and three repeat multicountry cross-sectional surveys. Lancet 2006;368:733-43.  Back to cited text no. 17
    
18.
Mohammadbeigi A, Hassanzadeh J, Mousavizadeh A. Prevalence of asthma in elementary school age children in Iran – A systematic review and meta analysis study. Pak J Biol Sci 2011;14:887-93.  Back to cited text no. 18
    
19.
Lee SI. Prevalence of childhood asthma in Korea: International study of asthma and allergies in childhood. Allergy Asthma Immunol Res 2010;2:61-4.  Back to cited text no. 19
    
20.
Momen T, Saffari M, Jari M, Shahsanai A, Sayedi SJ. Survey on the prevalence of allergic rhinitis in junior high school students in Isfahan, Iran. Int J Pediatr 2018;6:8253-60.  Back to cited text no. 20
    
21.
Safari M, Jarri M. Prevalence of allergic rhinitis in 13-14 year-old students of Hamedan. Iranian J Pediatrics 2008;18(Suppl 1):41-6.  Back to cited text no. 21
    
22.
Chong SN, Chew FT. Epidemiology of allergic rhinitis and associated risk factors in Asia. World Allergy Organ J 2018;11:17.  Back to cited text no. 22
    
23.
Mehanna N, Mohamed N, Wordofa M, Abera D, Mesfin A, Wolde M, et al. Allergy-related disorders (ARDs) among ethiopian primary school-aged children: Prevalence and associated risk factors. PLoS One 2018;13:e0204521.  Back to cited text no. 23