Superimposed Hepatitis C Virus in Sickle Cell Disease Pregnant Woman

Document Type : CASE REPORT


1 Department of Obstetrics and Gynecology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

2 Department of General Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran


Sickle cell disease (SCD) is a hereditary blood disorder that can increase complications during pregnancy and in turn negatively influence pregnancy outcomes. In addition to patients with SCD are at a high risk of been infected with hepatitis C infection. Furthermore in this study, we reported the clinical status of a pregnant woman with SCD who had hepatitis C virus infection.


Desai G, Anand A, Shah P, Shah S, Dave K, Bhatt H, et al. Sickle cell disease and pregnancy outcomes: A study of the community-based hospital in a tribal block of Gujarat, India. J Health Popul Nutr 2017;36:3.  Back to cited text no. 1
Boafor TK, Olayemi E, Galadanci N, Hayfron-Benjamin C, Dei-Adomakoh Y, Segbefia C, et al. Pregnancy outcomes in women with sickle-cell disease in low and high income countries: A systematic review and meta-analysis. BJOG 2016;123:691-8.  Back to cited text no. 2
Patel B, Coviello E, Shenoy A. Pregnancy in women with sickle cell disease. Blood 2017;130 Suppl 1:4801.  Back to cited text no. 3
Grossetti E, Carles G, El Guindi W, Seve B, Montoya Y, Creveuil C, et al. Selective prophylactic transfusion in sickle cell disease. Acta Obstet Gynecol Scand 2009;88:1090-4.  Back to cited text no. 4
Villers MS, Jamison MG, De Castro LM, James AH. Morbidity associated with sickle cell disease in pregnancy. Am J Obstet Gynecol 2008;199:125.e1-5.  Back to cited text no. 5
Winder AD, Johnson S, Murphy J, Ehsanipoor RM. Epidural analgesia for treatment of a sickle cell crisis during pregnancy. Obstet Gynecol 2011;118:495-7.  Back to cited text no. 6
Larrabee KD, Monga M. Women with sickle cell trait are at increased risk for preeclampsia. Am J Obstet Gynecol 1997;177:425-8.  Back to cited text no. 7
Seaman CD, Yabes J, Li J, Moore CG, Ragni MV. Venous thromboembolism in pregnant women with sickle cell disease: A retrospective database analysis. Thromb Res 2014;134:1249-52.  Back to cited text no. 8
Kavitha B, Hota BH. Sickle cell disease complicating pregnancy: A retrospective study. J Drug NTR Univ Health Sci 2017;6:242.  Back to cited text no. 9
Yadufashije, Dr. Callixte and Sangano, George Bahati and Samuel, Rebero, Prevalence of Sickle Cell Disease in Pregnant Women and Neonates in Africa. International Journal of Interdisciplinary Innovative Research and Development (IJIIRD), 2017;2:1-5.  Back to cited text no. 10
Su GL. Hepatitis C in pregnancy. Curr Gastroenterol Rep 2005;7:45-9.  Back to cited text no. 11
Webster DP, Klenerman P, Dusheiko GM. Hepatitis C. Lancet 2015;385:1124-35.  Back to cited text no. 12