A Novel Algorithm in Radiation Dosimetry of Regular and Irregular Treatment Fields

Document Type : Original Article

Authors

1 Department of Radiotherapy and Oncology, Ayatollah Khansari Hospital, Arak, Iran

2 Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

3 Department of Medical Physics, School of Medicine, Arak University of Medical Sciences, Arak, Iran

Abstract

Background: The aim of this study was to design an algorithm for the calculation of monitor unit (MU) in a short time and high precision for different radiotherapy (RT) fields. Materials and Methods: The algorithm for calculating MU for the stated patients was designed in MATLAB software. To investigate the efficiency of this algorithm, 11 regular chest fields with the sizes of 7 cm × 7 cm up to 17 cm × 17 cm were considered, and the obtained MUs were compared with MUs of 13 patients which were calculated with a “hand calculation” which is used in some RT centers for the aforementioned fields. Results: The maximum percentage of calculation errors of regular fields at the depths of 4 and 10 cm were 1 and 0.8, respectively. The maximum and minimum percentage of calculation errors in irregular fields was 3 and 0.9, respectively. Furthermore, the maximum and minimum errors were 8.8 and 0.14, respectively. In addition, relative percentages of the MUs for irregular fields of chest and supraclavicular were 1.63 and 1.01, respectively. Conclusion: Calculation of MUs is suggested to be performed with the novel proposed algorithm, due to reduce the treatment time, and also provide high accuracy and precision compared to hand calculation.

Keywords

1.
Al Amri I, Ravichandran R, Sivakumar SS, Binukumar JP, Davis CA, Al Rahbi Z, et al. Radiotherapy pre-treatment dose validation: A second verification of monitor units (MU) with a commercial software. J Med Phys 2012;37:235-9.  Back to cited text no. 1
    
2.
Alaei P, Higgins P. Effect of multileaf collimator-defined segment size on S (c). Med Phys 2010;37:2731-7.  Back to cited text no. 2
    
3.
Georg D, Olofsson J, Künzler T, Karlsson M. On empirical methods to determine scatter factors for irregular MLC shaped beams. Med Phys 2004;31:2222-9.  Back to cited text no. 3
    
4.
Intensity Modulated Radiation Therapy Collaborative Working Group. Intensity-modulated radiotherapy: Current status and issues of interest. Int J Radiat Oncol Biol Phys 2001;51:880-914.  Back to cited text no. 4
    
5.
Van Dyk J. Quality assurance of radiation therapy planning systems: Current status and remaining challenges. Int J Radiat Oncol Biol Phys 2008;71:S23-7.  Back to cited text no. 5
    
6.
Gibbons JP, Reft CS. Monitor unit calculations for external photon and electron beams. Med Phys 2002;29:106-7.  Back to cited text no. 6
    
7.
Khan FM, Gibbons JP. Khan's the Physics of Radiation Therapy. 5 th eddition: Lippincott Williams & Wilkins; 2014.  Back to cited text no. 7
    
8.
Healy BJ, Murry RL. Testing of a treatment planning system with beam data from IAEA TECDOC 1540. J Med Phys 2011;36:107-10.  Back to cited text no. 8
[PUBMED]  [Full text]  
9.
Salomons G, Kelly D. Software safety in radiation therapy. J Med Phys 2013;38:1-3.  Back to cited text no. 9
[PUBMED]  [Full text]  
10.
Taheri H, Tavakoli MB, Akhavan A. Radiobiological evaluation of three common clinical radiotherapy techniques including combined photon-electron, tangential beams and electron therapy in left-sided mastectomy patients. Adv Biomed Res 2018;7:99.  Back to cited text no. 10
    
11.
Muren LP, Maurstad G, Hafslund R, Anker G, Dahl O. Cardiac and pulmonary doses and complication probabilities in standard and conformal tangential irradiation in conservative management of breast cancer. Radiother Oncol 2002;62:173-83.  Back to cited text no. 11
    
12.
Tavakoli M, Taheri H, Akhavan A. Measurement of ipsilateral lung and heart dose in radiotherapy of left sided mastectomy patients in common different clinical techniques: A phantom study. Int J Radiat Res 2018;16:389-94.  Back to cited text no. 12
    
13.
Lu L. Dose calculation algorithms in external beam photonradiation therapy. Int J Cancer Ther Oncol 2013; 1 (2):01025  Back to cited text no. 13
    
14.
Ahnesjö A, Aspradakis MM. Dose calculations for external photon beams in radiotherapy. Phys Med Biol 1999;44:R99-155.  Back to cited text no. 14
    
15.
De Jaeger K, Hoogeman MS, Engelsman M, Seppenwoolde Y, Damen EM, Mijnheer BJ, et al. Incorporating an improved dose-calculation algorithm in conformal radiotherapy of lung cancer: Re-evaluation of dose in normal lung tissue. Radiother Oncol 2003;69:1-0.  Back to cited text no. 15
    
16.
Golestani A, Houshyari M, Mostaar A, Arfaie AJ. Evaluation of dose calculation algorithms of isogray treatment planning system using measurement in heterogeneous phantom. Rep Radiother Oncol 2015;2: e5320.  Back to cited text no. 16
    
17.
Miften MM, Beavis AW, Marks LB. Influence of dose calculation model on treatment plan evaluation in conformal radiotherapy: A three-case study. Med Dosim 2002;27:51-7.  Back to cited text no. 17
    
18.
Sellakumar P, Arun C, Sanjay SS, Ramesh SB. Comparison of monitor units calculated by radiotherapy treatment planning system and an independent monitor unit verification software. Phys Med 2011;27:21-9.  Back to cited text no. 18
    
19.
Gibbons JP, Antolak JA, Followill DS, Huq MS, Klein EE, Lam KL, et al. Monitor unit calculations for external photon and electron beams: Report of the AAPM Therapy Physics Committee Task Group No 71. Med Phys 2014;41:301-501.  Back to cited text no. 19