Nutrition Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

Document Type : CASE REPORT


Department of Clinical Toxicology, School of Medicine, Noor Hospital, Isfahan University of Medical Sciences, Isfahan, Iran


Paraquat is a highly toxic compound and a widely used herbicide that causes serious morbidity and mortality. The most well-known route of poisoning is oral ingestion, whereas parenteral injection of paraquat is individually uncommon. We present a case who injected paraquat in his neck in an attempt to commit suicide. His general condition got worsened gradually over 3 days. He received early hemodialysis in 4 h after self-injection and then supportive treatment in intensive care unit. Early hemodialysis helped him survive, but during hospitalization, some rare complications occurred, and unfortunately, he died after 3 months. Despite the high-risk route of poisoning, the patient survived for 3 months. Our patient was protected from renal and hepatic damage may be because of early hemodialysis but suffered from central nervous system and pulmonary damage.


Phuinthiang P, Kajitvichyanukul P. Degradation of paraquat from contaminated water using green TiO2 nanoparticles synthesized from Coffea arabica L. in photocatalytic process. Water Sci Technol 2019;79:905-10.  Back to cited text no. 1
Bismuth C, Garnier R, Baud FJ, Muszynski J, Keyes C. Paraquat poisoning. An overview of the current status. Drug Saf. 1990;5(4):243-51.  Back to cited text no. 2
Almog C, Tal E. Death from paraquat after subcutaneous injection. Br Med J 1967;3:721.  Back to cited text no. 3
Chen HW, Tseng TK, Ding LW. Intravenous paraquat poisoning. J Chin Med Assoc 2009;72:547-50.  Back to cited text no. 4
Choi Y, Cho K, Yoon S, Lee H, Choi Y. A case of paraquat intoxication caused by intravenous injection. Am J Emerg Med 2008;26:836.e3-4.  Back to cited text no. 5
Fernando R. Survival of a patient after self-injection of paraquat and surgical excision of the injection site. Ceylon Med J 2015;60:66.  Back to cited text no. 6
Chen CW, Wu YH, Chien SC, Lin JC. A survival case of intravenous paraquat intoxication: A case report. Medicine (Baltimore) 2018;97:e11669.  Back to cited text no. 7
Yen TH, Wang IK, Hsu CW. Hemoperfusion for paraquat poisoning. Kidney Int 2018;94:1239.  Back to cited text no. 8
Huang C, Zhang X, Jiang Y, Li G, Wang H, Tang X, et al. Paraquat-induced convulsion and death: A report of five cases. Toxicol Ind Health 2013;29:722-7.  Back to cited text no. 9
Fernandez P, Bermejo AM, Lopez-Rivadulla M, Cruz A, Rodriguez E, Otero A. A fatal case of parenteral paraquat poisoning. Forensic Sci Int 1991;49:215-24.  Back to cited text no. 10
Hsu HH, Chang CT, Lin JL. Intravenous paraquat poisoning-induced multiple organ failure and fatality-A report of two cases: Case report. J Toxicol Clin Toxicol 2003;41:87-90.  Back to cited text no. 11
Elenga N, Merlin C, Le Guern R, Kom-Tchameni R, Ducrot YM, Pradier M, et al. Clinical features and prognosis of paraquat poisoning in French Guiana: A review of 62 cases. Medicine (Baltimore) 2018;97:e9621.  Back to cited text no. 12