Advanced Biomedical Research
Original Article: Bone densitometry and fat index after sleeve and subsleeve gastrectomy in animal model
Authors
- Hajar Khazraei 1
- Seyed Vahid Hosseini 1
- Masood Amini 2
- Saeed Amirzadeh 3
- Amirreza Dehghanian 4
- Zahra Sobhani 2
- Hengameh Kasraei 5
1 Colorectal Research Center, Shiraz University of Medical Sciences
2 Laparoscopic Research Center, Shiraz University of Medical Sciences
3 Gastroentrohepatology Research Center, Shiraz University of Medical Sciences
4 Molecular Pathology and Cytogenetics Division, Shiraz University of Medical Sciences
5 Colorectal Research Center, Shiraz University of Medical Sciences. General Physician Faculty of Medicine, Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran
Abstract
Background: Previous studies have reported that gastrectomy and fundectomy can induce osteopenia. Body fat index is a new index of obesity that shows central obesity and other risks of obesity. Sleeve gastrectomy (SG) is a bariatric surgery and a new technique introduced as subsleeve, which only resected fundus of the stomach. In this study, it has been shown the effect of subsleeve and SG on fat index and bone densitometry in an animal model. Materials and Methods: Rabbits were underlined SG, fundectomy (surgical removal of fundus), or sham-operated (controls without any resection), and after 12 weeks, fat index and bone densitometry were obtained. Results: Our study showed that there was no significant difference between SG and fundectomy groups in bone mass density and fat mass after surgery in comparison with presurgery condition. SG group were associated with lower fat index and bone density, and it showed significantly decrease in weight after 1.5 months. Conclusion: Sub-SG did not show any significant effect on fat index and bone densitometry in comparison with SG. However, we found lower fat index in sleeve group of rabbits, but it was not statistically significant.
Keywords
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