Advanced Biomedical Research 2277-9175 2014 october 2014 10 01 The comparative study of Yaz and Ovocept-ld on patients with simple ovarian cysts referring to Iran-Isfahan Shariati Hospital 1 5 30540 EN Soheyla Riahinejad Department of Medical Sciences, Nursing and Midwifery College, Islamic Azad University, Najafabad Branch, Isfahan, Iran Azam Foroughi Pour Department of Medical Sciences, Nursing and Midwifery College, Islamic Azad University, Najafabad Branch, Isfahan, Iran Leila Dehghani Department of Medical Sciences, Nursing and Midwifery College, Islamic Azad University, Najafabad Branch, Isfahan, Iran Saadat Hajizadeh Faculty of Midwifery Group, Nursing and Midwifery College, Islamic Azad University, Najafabad Branch, Isfahan, Iran Journal Article 2023 04 10 <strong>Background:</strong> Functional ovarian cysts include follicular, corpus luteum, and theca lutein cysts are the most common adnexal masses (about 50%) in women of reproductive age. Treatment with the combined monophasic oral contraceptives reduces functional ovarian cysts. Yaz (drospirenone/ethinyl estradiol) is a low-dose combined oral contraceptive pill containing 20 μg ethinyl estradiol and 3 mg drospirenone. In addition to contraceptive effects, Yaz has anti-mineralocorticoid and anti-adrenergic effects. Ovocept- low-dose LD is also a low-dose combined oral contraceptive drug containing 30 μg ethinyl estradiol and 3 mg norgestrol. Ovocept-LD has some side-effects such as weight gain, spotting, breast tenderness, nausea, and headache.<br /><strong>Materials</strong> <strong>and</strong> <strong>Methods:</strong> Being a clinical study, the present research was carried out on 42 patients with the simple ovarian cysts from 2010 to 2012. 84 Patients were assigned to A and B groups. Group A received Yaz once a day for a period of 28 days and group B received Ovocept-LD once a day for a period of 21 days. After treating by Yaz and Ovocept-LD, Cysts were evaluated by ultrasound. Results were analyzed by the SPSS software. A P < 0.05 was considered the significance threshold.<br /><strong>Results</strong> : Obtained results indicated that both Yaz and Ovocept-LD had an effect on the simple ovarian cysts. Statistical tests, however, has shown that the effect of Yaz has been significantly more than that of Ovocept-LD.<br /><strong>Conclusion:</strong> Given the faster and better recovery effect, and the lesser side effects of Yaz as compared to Ovocept-LD, it is recommended to use Yaz for the simple ovarian cysts. https://advbiores.mui.ac.ir/article_30540_5dd0565bef8f4fb788527a171d688538.pdf